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The 2021-2023 picture for University of California, Irvine Department of Physiology and Biophysics is a 21-PI network with 10 internal PI collaborations. The research center of gravity is Medicine as the leading field (36% of slots across 15 PIs; 15 labels), Molecular Biology as the leading subfield (11% of slots across 6 PIs; 6 labels), and Ion channel regulation and function as the leading topic (5% of slots across 3 PIs; 3 labels). That is a thin collaboration pattern, useful for spotting individual pairs but less persuasive as a broad departmental network. The top weighted PIs are Geoffrey W. Abbott (11.8 weighted works; Ion channel regulation and function, Cardiac electrophysiology and arrhythmias); Lan Huang (10 weighted works; Advanced Proteomics Techniques and Applications, Mass Spectrometry Techniques and Applications). The strongest pairings are Lisa E. Wagar and D. Huw Davies (3 shared works, weight 1.6). The standout breakdown groups are group 1 with 3 PIs, 2 internal connections, weight 1.2, around Neurology, Spectroscopy, Infectious Diseases, led by Lan Huang, Rongsheng Jin, Qin Yang.